New Study Predicts Immune Protection May Vary For Different Covid-19 Vaccines

After more than a year of lockdowns, isolation, and great loss of human life, the slow but steady rollout of Covid-19 vaccines has given us all a much-needed glimmer of hope. As of March 22, the total number of doses administered worldwide is nearing 500 million, with millions more to come as the eligibility pool expands from high priority groups to the broader population.

But for all the progress being made, much remains unknown about how protected people really are—and how long that protection will last—once they’re vaccinated, especially now that more infectious and immunologically challenging variants of SARS-CoV-2 are on the loose. Though it will be some time before we have long-term clinical data on vaccinees that can answer these questions definitively, a new preprint study has taken the first step by using predictive modeling techniques to estimate the strength and length of immune protection conferred by seven different vaccines over time. The results suggest that the more protective a vaccine is immediately following immunization, the longer protection will last. More than that, however, they imply we’ll have to retool our vaccine strategies so they better address the issue of waning immunity against Covid-19.

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Originally published on Forbes (March 25, 2021)

© William A. Haseltine, PhD. All Rights Reserved.