Omicron: The Sum Of All Fears!

This is the first of a two-part series. Here we describe the mutations in the Omicron Spike protein. In part two, we will describe mutations in other parts of the genome.

A new variant, Omicron, very effectively evades the neutralizing antibodies of the Pfizer vaccine regimen, according to a recent study. The research by Cele et al. demonstrates that neutralization protection dropped over 40-fold against the Omicron variant as compared to the D614G Triad strain. This includes those with the highest protection, having been previously infected and then two-dose vaccinated with the Pfizer vaccine. In other words, a two-dose regimen of the Pfizer vaccine will not protect against Omicron. Whether three doses is protective, we do yet not know.

The Omicron variant has the potential to spark the next great wave of SARS-CoV-2. Dozens of countries are on high alert as Omicron sequence detection is rapidly increasing. Case numbers are expected to rise dramatically in the coming days and weeks. See the rise of the Omicron variant in South Africa and globally below.

Read the full article on Forbes.

© William A. Haseltine, PhD. All Rights Reserved.