SARS-CoV-2 Immunity: A Moving Target

The ability of newly discovered variants to reinfect those who have recovered from earlier Covid-19 infection or those immunized with Covid vaccines is a hot topic. The two strains receiving the most attention are the SARS-CoV-2 variants from the United Kingdom (B.1.1.7) and South Africa (B.1.351). There is mounting evidence that they may be resistant to neutralization by antibodies directed against earlier stains. Definitive proof of resistance can be accomplished by measuring the neutralizing activity of antibodies in the sera from patients infected in the early months of 2020 against both the original and the variant viruses. Scientists from Chongqing Medical University, China did just that in this study. They tested the activity of antibodies in the sera of twenty patients at two time points, in February and October. These patients were infected with SARS-CoV-2 in January and early February. Read the full article on Forbes.
© William A. Haseltine, PhD. All Rights Reserved.