Variants: Forewarned Is Forearmed— For Those Who Listen

We now know the adaptive power of SARS-CoV-2 variants. Newly described Covid-19 variants isolated in the United Kingdom, South African, Brazil, the United States, and Nigeria appear to be more transmissible, resist neutralization. and may be more virulent. Now turn back the wheels of time. Were we to know about this variant future, perhaps we could have been prepared. As it turns out, one scientist, Dr. Li Lanjuan, and her colleagues at Zhejiang University provided that early warning.

In a set of two papers released in March and April 2020, Dr. Lanjuan revealed what today is common knowledge. After deep sequencing patients from Hangzhou, Lanjuan identified a series of mutations in the genome and specifically in the spike protein. Her studies spelled out the potential dangers of rapidly mutating virus, one that not only could change,  but a change in critical regions that could affect how well the virus might be transmitted and its potential to cause severe disease.

Read the full article on Forbes.

© William A. Haseltine, PhD. All Rights Reserved.