Writings OLD
July 23, 2024
A study published in Nature suggests a variation in responses to a cancer immunotherapy called checkpoint inhibitors may be due—at least in part—to a patient’s intestinal microbiome.
Turning to the Intestines
There are other similar reports that paint a connection between the microbiome—the collection of microorganisms … read more
July 23, 2024
In a world where an aging population faces increasing health challenges, a silent epidemic is quietly eroding the quality of life for millions. Osteoporosis affects one in three women and one in five men over 50 worldwide, weakening bones and leaving them vulnerable to life-altering fractures. However, as the … read more
July 20, 2024
When it comes to aging, many factors are at play, from lifestyle choices to genetic makeup. One of the key players in this complex process is something you might not have heard much about: telomeres. These tiny structures, found at the ends of our chromosomes, are crucial to our understanding … read more
July 17, 2024
In a world where weight loss methods range from trendy diets to prescription medications, a new genetic study offers a fresh perspective. A rare genetic variation has been found to shield individuals from gaining weight, even on a high-fat diet. This enhances our understanding of the genetic factors behind obesity … read more
July 16, 2024
PD-1 checkpoint proteins on T cells (blue) can bind to two different receptors: PD-L1 and PD-L2.
ACCESS HEALTH INTERNATIONAL There are many ways to climb a mountain. This saying especially rings true in cancer research, where scientists are probing several avenues to combat tumors. One promising strategy involves checkpoint inhibitors, … read moreJuly 9, 2024
Solid tumors are notoriously difficult to suppress. They survive and thrive in the body despite best efforts to control them—resisting even the latest immunotherapies such as PD-1 and PD-L1 targeting checkpoint inhibitors. One of the ways researchers are trying to address this problem is by disarming the tumor’s defenses against … read more
July 7, 2024
One of the most significant hurdles to providing gene therapies for hearing loss is access to the inner ear. Our ears are intricate and feature complex structures that make getting treatment into the cochlea difficult. Recently, a study led by Mathiesen and colleagues has unveiled a novel method for … read more
July 4, 2024
Abstract
Coronaviruses constitute a global threat to human and animal health. It is essential to investigate the long-distance RNA-RNA interactions that approximate remote regulatory elements in strategies, including genome circularization, discontinuous transcription, and transcriptional enhancers, aimed at rapid replication of their large genomes, pathogenicity, and immune evasion. Based on the primary … read more
July 1, 2024
Originally published October 23, 2023.
Almost four decades ago, the characterization of the human immunodeficiency virus type 1 (HIV-1) genome with the participation of the Haseltine laboratory at Harvard Medical School (Ratner et al., 1985) ushered in the antiretroviral era and established the framework for the genomic- and later multiple omics-based … read more
July 1, 2024